SYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF SUBSTITUTED PYRAZOLINES FROM 2-ACETYLFLUORENE BASED CHALCONE

Objective: The present work is based on the above pyrazoline derivative form heterocyclic substituted chalcone. Methods: elemental analysis, IR, 1H and 13C NMR mass spectrum analyses were used to characterise structures of obtained compounds. Results: scheme-1 scheme-2 describe synthesis chalcone (thiophene-fluorenyl derivative) pyrazolines respectively. Chalcone has been synthesized from 2-Acetylfluorene, which had reacted with phenylhydrazine, 4-substituted phenylhydrazine (4-Chloro 4-Nitro) 2,4-Dinitrophenylhydrazine (CP01-CP04). Conclusion: antimicrobial antioxidant properties evaluated those newly synthesised